ESSENTIAL EUKARYOTIC CORE
نویسندگان
چکیده
منابع مشابه
Eukaryotic transcription: The core of eukaryotic gene activation
Gene expression is controlled by interactions between activators and coactivators. These interactions in turn are regulated by signaling pathways and by chromatin remodeling events. Recent studies indicate that the final arbiter of gene regulation is a coactivator scaffold at the promoter.
متن کاملPutative essential and core-essential genes in Mycoplasma genomes
Mycoplasma, which was used to create the first "synthetic life", has been an important species in the emerging field, synthetic biology. However, essential genes, an important concept of synthetic biology, for both M. mycoides and M. capricolum, as well as 14 other Mycoplasma with available genomes, are still unknown. We have developed a gene essentiality prediction algorithm that incorporates ...
متن کاملGeneric eukaryotic core promoter prediction using structural features of DNA.
Despite many recent efforts, in silico identification of promoter regions is still in its infancy. However, the accurate identification and delineation of promoter regions is important for several reasons, such as improving genome annotation and devising experiments to study and understand transcriptional regulation. Current methods to identify the core region of promoters require large amounts...
متن کاملCharacterization of Eukaryotic Core Promoters Based on Nonlinear Dimensionality Reduction
Characterization and identification of eukaryotic promoter is important for the gene prediction and genome annotation. In this paper, we study the structural characteristics of the core promoters in several eukaryotes through a series of DNA physicochemical properties and adopt a method that combines the alignment and average of multiple promoters and the nonlinear dimensionality reduction tech...
متن کاملProkaryotic and eukaryotic RNA polymerases have homologous core subunits.
Eukaryotic RNA polymerases are complex aggregates whose component subunits are functionally ill-defined. The gene that encodes the 140,000-dalton subunit of Saccharomyces cerevisiae RNA polymerase II was isolated and studied in detail to obtain clues to the protein's function. This gene, RPB2, exists in a single copy in the haploid genome. Disruption of the gene is lethal to the yeast cell. RPB...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Evolution
سال: 2004
ISSN: 0014-3820
DOI: 10.1111/j.0014-3820.2004.tb01660.x